Arsenic is a xenobiotic metalloid that has become a major environment pollutant. As many as 70 million people in the Indo-Bangladesh region are exposed to inorganic arsenic through consumption of water soluble arsenic salts in drinking water. This has resulted in a number of adverse health outcomes which include melanosis, hyperkeratosis which can later lead to Bowen’s disease, basal cell and squamous cell carcinomas.  Our laboratory, for the first time, has demonstrated that garlic, a major component of Indian diet, has the capacity to reduce arsenic induced toxicity both in-vitro and in-vivo. The sulphur-containing substances in garlic scavenge arsenic from tissues and blood, which could be a potential remediation of arsenic toxicity for people in at risk areas. Presently, the laboratory has been analyzing the efficacy of the different components of garlic for remediation of arsenic toxicity.