Pathogenesis of Vibrio cholerae



• Vibrio cholerae O395 outer membrane vesicles modulate intestinal epithelial Cells in a NOD1 dependent manner and induces dendritic cell-mediated Th2/Th17 responses. (2013). Chatterjee D, Chaudhuri K. Journal of Biological Chemistry (In press) PMID 23275338, DOI: 10.1074/jbc.M112.408302.

• Interleukin-8 gene regulation in epithelial cells by Vibrio cholerae: Role of multiple promoter elements, adherence and motility of bacteria and host MAPKs. (2012). Sarkar M, Bhowmick S, Casola A, Chaudhuri K. FEBS Journal Apr;279(8):1464-1473. Doi: 10.1111/j.1742-4658.2012.08539.x.  Epub 2012 Mar 14. PMID: 22348317.

• Human epithelial cells stimulated with Vibrio cholerae produce thymic stromal lymphopoetin and promote dendritic cell-mediated inflammatory Th2 response. (2012). Bhowmick S, Chatterjee D and Chaudhuri K. International Journal of Biochemistry & Cell Biology 44: 1779-1790.PMID:22750414.

• Association of cholera toxin with Vibrio cholerae outer membrane vesicles which are internalized by human intestinal epithelial cells. (2011). Chatterjee D and Chaudhuri K. FEBS Letters 585:1357-1362.

• Involvement of intracellular signaling cascades in inflammatory responses in human intestinal epithelial cells following Vibrio cholerae infection. (2009). Bandyopadhaya A, Das D and Chaudhuri K. Molecular Immunology 46:1129-1139.

• Differential modulation of NF-kB mediated proinflammatory response in human intestinal epithelial cells by cheY homologues of Vibrio cholerae. (2009). Bandyopadhaya A and Chaudhuri K. Innate Immunity 15(3):131-142.

• Activation of proinflammatory response in human intestinal epithelial cells following Vibrio cholerae infection through PI3K/Akt pathway. Bandyopadhaya A, Bhowmick S and Chaudhuri K. (2009). Canadian Journal of Microbiology 55(11):1310-1318.

• IL-1β expression in Int407 is induced by flagellin of Vibrio cholerae through TLR5 mediated pathway. (2008). Bandyopadhaya A, Sarkar M and Chaudhuri K. Microbial Pathogenesis 44:524-36.

• Identification of a new RTX like gene cluster in Vibrio cholerae. (2008) Chatterjee R., Nag S and Chaudhuri K. FEMS Microbiology Letters 284:165-171.

• Human intestinal epithelial cell cytokine mRNA responses mediated by NF-kappaB are modulated by the motility and adhesion process of Vibrio cholerae (2007) Bandyopadhaya A, Sarkar M and Chaudhuri K. International Journal of Biochemistry and Cell Biology 39:1863-76.

• Transcriptional upregulation of inflammatory cytokines in human intestinal epithelial cells following Vibrio cholerae infection. Bandyopadhaya A, Sarkar M and Chaudhuri K. (2007) FEBS Journal 274:4631-4642.

• Differential regulation of inter-chromosomal copies of ToxR-induced genes. Nag S and Chaudhuri K. (2007). Canadian Journal of Microbiology 53:992-999. 

• In vivo induced clpB1 gene of Vibrio cholerae is involved in different stress responses and affects in vivo cholera toxin production. (2005). Nag S, Das S and Chaudhuri K. Biochemical and Biophysical Research Communications 331:1365-1373.

• Upregulation of human mitochondrial NADH dehydrogenase subunit 5 in intestinal epithelial cells is modulated by Vibrio cholerae pathogenesis. (2005). Sarkar M, Das S, Bandyopadhyay A, Ray K and Chaudhuri K. FEBS Letters 579:3449-60.

• Association of adherence and motility in interleukin 8 induction in human intestinal epithelial cells by Vibrio cholerae. (2004). Sarkar M and Chaudhuri K.  Microbes and Infection 6:676-685.

• Identification of a unique IAHP (IcmF Associated Homologous Proteins) cluster in Vibrio cholerae and other proteobacteria through in silico analysis. (2003). Das S and Chaudhuri K. In Silico Biology 3(3) 287-300.

• Involvement of in vivo induced icmF gene of Vibrio cholerae in motility, adherence to intestinal epithelial cells and conjugation frequency. (2002). Das S, Chakrabortty A, Banerjee R and Chaudhuri K. Biochemical and Biophysical Research Communications 295:922-928.

• Involvement of in vivo induced cheY-4 gene of Vibrio cholerae in motility, early adherence Mukhopadhyay, K, Nag, S, Chakrabortty, A and Chaudhuri, K. FEBS Letters 532:221-226.

• Lessons to be learnt from Vibrio cholerae in model systems. (2001). Chaudhuri K. Genome Biology 2(8): interactions 1003.1-1003.2.

• Use of RNA arbitrarily primed PCR fingerprinting to identify Vibrio cholerae genes differentially expressed in host following infection. (2000). Chakrabortty A, Das S, Majumdar S, Mukhopadhyay K, Roychoudhury S, Chaudhuri K. Infection and Immunity 68:3878-3887.

• Comparison of global transcription responses allows identification of Vibrio cholerae genes differentially expressed following infection. (2000). Das S, Chakrabortty A, Banerjee R, Roychoudhury S and Chaudhuri K. FEMS Microbiology Letters 190:87-91.

• Porins of Vibrio cholerae:Purification and characerisation of OmpU. (1996). Chakrabarti SR, Chaudhuri K, Sen K and Das J. Journal of Bacteriology 178:524-530.

• Presence of exposed phospholipids in the outer membrane of Vibrio cholerae. (1992). Paul S, Chaudhuri K, Chatterjee AN and Das J. Journal of General Microbiology 138:755-761.

• Interaction of Vibrio cholerae with beta-lactam antibiotics: Emergence of resistant cells at a high frequency. (1992). Sengupta TK, Chaudhuri K, Majumdar S, Lohia A, Chatterjee AN and Das J. Antimicrobial Agents and Chemotherapy 36:788-795.

• Cell surface of environmental and clinical isolates of Vibrio cholerae non-O1. (1992). Chaudhuri K, Bhadra RK and Das J. Applied and Environmental Microbiology 58:3567-3573.

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Cholera bacteriophages


• Structural polypeptides of cholera bacteriophage phi 2. (1981). Chaudhuri K and Maiti M. Canadian Journal of Microbiology 27:72-75.

• Spectrophotometric characteristics of choleraphage phi 2 DNA. (1980). Chaudhuri K and Maiti M. Journal of General Virology 49:433-436.

• Interaction of bacteriophage phi 149 with Vibrios. (1980). Maiti M and Chaudhuri K. Indian Journal of Biochemistry and Biophysics 17:72-73.

• Genome and structural protein characterization of Vibrio phage phi 2. (1980). Chaudhuri K and Maiti M. Indian Journal of Biochemistry and Biophysics 17:207-212.

• Some properties of a Vibrio cholerae bacteriophage phi 2. (1979). Maiti M and Chaudhuri, K. Indian Journal of Experimental Biology 17: 628-631.